An experimental model for the study of lymphedema and its response to therapeutic lymphangiogenesis.
Identifieur interne : 007A44 ( Main/Exploration ); précédent : 007A43; suivant : 007A45An experimental model for the study of lymphedema and its response to therapeutic lymphangiogenesis.
Auteurs : Lauren Cheung [États-Unis] ; Jennifer Han ; Andreas Beilhack ; Smita Joshi ; Paul Wilburn ; Aman Dua ; Andrew An ; Stanley G. RocksonSource :
- BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy [ 1173-8804 ] ; 2006.
Descripteurs français
- KwdFr :
- Animaux, Facteur de croissance endothéliale vasculaire de type A (pharmacologie), Femelle, Glycoprotéines (métabolisme), Immunohistochimie, Lymphangiogenèse (), Lymphoedème (), Lymphoedème (anatomopathologie), Lymphoedème (immunologie), Lymphoedème (métabolisme), Maladie aigüe, Modèles animaux de maladie humaine, Souris, Transport de protéines.
- MESH :
- anatomopathologie : Lymphoedème.
- immunologie : Lymphoedème.
- métabolisme : Glycoprotéines, Lymphoedème.
- pharmacologie : Facteur de croissance endothéliale vasculaire de type A.
- Animaux, Femelle, Immunohistochimie, Lymphangiogenèse, Lymphoedème, Maladie aigüe, Modèles animaux de maladie humaine, Souris, Transport de protéines.
English descriptors
- KwdEn :
- Acute Disease, Animals, Disease Models, Animal, Female, Glycoproteins (metabolism), Immunohistochemistry, Lymphangiogenesis (drug effects), Lymphedema (immunology), Lymphedema (metabolism), Lymphedema (pathology), Lymphedema (therapy), Mice, Protein Transport, Vascular Endothelial Growth Factor A (pharmacology).
- MESH :
- chemical , metabolism : Glycoproteins.
- drug effects : Lymphangiogenesis.
- immunology : Lymphedema.
- metabolism : Lymphedema.
- pathology : Lymphedema.
- chemical , pharmacology : Vascular Endothelial Growth Factor A.
- therapy : Lymphedema.
- Acute Disease, Animals, Disease Models, Animal, Female, Immunohistochemistry, Mice, Protein Transport.
Abstract
Evaluation of the efficacy of molecular treatment strategies for lymphatic vascular insufficiency requires a suitable preclinical animal model. Ideally, the model should closely replicate the untreated human disease in its pathogenesis and pathological expression.
PubMed: 17176124
Affiliations:
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Le document en format XML
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<author><name sortKey="Cheung, Lauren" sort="Cheung, Lauren" uniqKey="Cheung L" first="Lauren" last="Cheung">Lauren Cheung</name>
<affiliation wicri:level="1"><nlm:affiliation>Division of Cardiovascular Medicine, Stanford Center for Lymphatic and Venous Disorders, Stanford University School of Medicine, Falk Cardiovascular Research Center, Stanford, California 94305, USA.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Division of Cardiovascular Medicine, Stanford Center for Lymphatic and Venous Disorders, Stanford University School of Medicine, Falk Cardiovascular Research Center, Stanford, California 94305</wicri:regionArea>
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<affiliation wicri:level="1"><nlm:affiliation>Division of Cardiovascular Medicine, Stanford Center for Lymphatic and Venous Disorders, Stanford University School of Medicine, Falk Cardiovascular Research Center, Stanford, California 94305, USA.</nlm:affiliation>
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<author><name sortKey="An, Andrew" sort="An, Andrew" uniqKey="An A" first="Andrew" last="An">Andrew An</name>
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<series><title level="j">BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy</title>
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<term>Animals</term>
<term>Disease Models, Animal</term>
<term>Female</term>
<term>Glycoproteins (metabolism)</term>
<term>Immunohistochemistry</term>
<term>Lymphangiogenesis (drug effects)</term>
<term>Lymphedema (immunology)</term>
<term>Lymphedema (metabolism)</term>
<term>Lymphedema (pathology)</term>
<term>Lymphedema (therapy)</term>
<term>Mice</term>
<term>Protein Transport</term>
<term>Vascular Endothelial Growth Factor A (pharmacology)</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Facteur de croissance endothéliale vasculaire de type A (pharmacologie)</term>
<term>Femelle</term>
<term>Glycoprotéines (métabolisme)</term>
<term>Immunohistochimie</term>
<term>Lymphangiogenèse ()</term>
<term>Lymphoedème ()</term>
<term>Lymphoedème (anatomopathologie)</term>
<term>Lymphoedème (immunologie)</term>
<term>Lymphoedème (métabolisme)</term>
<term>Maladie aigüe</term>
<term>Modèles animaux de maladie humaine</term>
<term>Souris</term>
<term>Transport de protéines</term>
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<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Glycoproteins</term>
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<keywords scheme="MESH" qualifier="anatomopathologie" xml:lang="fr"><term>Lymphoedème</term>
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<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Lymphangiogenesis</term>
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<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Lymphoedème</term>
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<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Lymphedema</term>
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<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Lymphedema</term>
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<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Glycoprotéines</term>
<term>Lymphoedème</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Lymphedema</term>
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<keywords scheme="MESH" qualifier="pharmacologie" xml:lang="fr"><term>Facteur de croissance endothéliale vasculaire de type A</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Vascular Endothelial Growth Factor A</term>
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<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Lymphedema</term>
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<term>Animals</term>
<term>Disease Models, Animal</term>
<term>Female</term>
<term>Immunohistochemistry</term>
<term>Mice</term>
<term>Protein Transport</term>
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<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Femelle</term>
<term>Immunohistochimie</term>
<term>Lymphangiogenèse</term>
<term>Lymphoedème</term>
<term>Maladie aigüe</term>
<term>Modèles animaux de maladie humaine</term>
<term>Souris</term>
<term>Transport de protéines</term>
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<front><div type="abstract" xml:lang="en">Evaluation of the efficacy of molecular treatment strategies for lymphatic vascular insufficiency requires a suitable preclinical animal model. Ideally, the model should closely replicate the untreated human disease in its pathogenesis and pathological expression.</div>
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<tree><noCountry><name sortKey="An, Andrew" sort="An, Andrew" uniqKey="An A" first="Andrew" last="An">Andrew An</name>
<name sortKey="Beilhack, Andreas" sort="Beilhack, Andreas" uniqKey="Beilhack A" first="Andreas" last="Beilhack">Andreas Beilhack</name>
<name sortKey="Dua, Aman" sort="Dua, Aman" uniqKey="Dua A" first="Aman" last="Dua">Aman Dua</name>
<name sortKey="Han, Jennifer" sort="Han, Jennifer" uniqKey="Han J" first="Jennifer" last="Han">Jennifer Han</name>
<name sortKey="Joshi, Smita" sort="Joshi, Smita" uniqKey="Joshi S" first="Smita" last="Joshi">Smita Joshi</name>
<name sortKey="Rockson, Stanley G" sort="Rockson, Stanley G" uniqKey="Rockson S" first="Stanley G" last="Rockson">Stanley G. Rockson</name>
<name sortKey="Wilburn, Paul" sort="Wilburn, Paul" uniqKey="Wilburn P" first="Paul" last="Wilburn">Paul Wilburn</name>
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<country name="États-Unis"><noRegion><name sortKey="Cheung, Lauren" sort="Cheung, Lauren" uniqKey="Cheung L" first="Lauren" last="Cheung">Lauren Cheung</name>
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